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Celiac Disease and Heredity

Some things that run in families, like Grandpa’s twinkly blue eyes or Aunt Mary’s dimpled cheeks are traits that we can look forward to seeing again and again in future generations. There are also genetic disorders that run in families, illnesses that we hope not to see in new additions to our families. Celiac disease, also referred to as Celiac sprue, is a genetic disorder that is characterized by an extreme immune response to gluten. At one time, Celiac disease was thought to be a rare childhood ailment. Today, however, as many as one in every one hundred and thirty three people are thought to have the disease. The tendency for Celiac disease to run in families is strong. One out of every twenty two people that has a first degree relative (parent, sibling, or child) is likely to be diagnosed with Celiac disease at some point in their lifetime.

Every time a person with Celiac disease ingests gluten, their immune system attacks the tiny villi inside of their small intestine, severely damaging them. When villi are being destroyed, nutrients from food can not be absorbed properly. If this goes on for long enough, malnutrition is likely.

People with Celiac disease can often experience a great deal of relief if they are able to successfully eliminate gluten from their diet. At first, it is very difficult to do this because gluten seems to be everywhere. Many people think of wheat when they hear the word gluten but gluten is also found in barley and rye, so people with Celiac disease can not tolerate these foods either. Gluten is actually pretty sneaky stuff and can be found in all sorts of places where you would not expect to find it, from Play Doh to vitamins, cosmetics, and more. Fortunately, with time and experience, gluten free living becomes easier.

As with many genetic disorders, if you have relatives with Celiac disease you may want to talk to your doctor so that together you can assess your level of risk.

Photo by Irish_Eyes on morguefile.com.